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AIM-100 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751554

MBS5751554 is an inhibitor targeting AIM-100. AIM-100 is a Ack1 inhibitor (IC50: 24nM). More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AIM-100, Inhibitor
Full Product Name
AIM-100
Product Gene Name
AIM-100, inhibitor
Product Synonym Names
AIM100; AIM 100
Form/Format
Powder
Purity/Purification
98.76%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
371.43
Formula
C23H21N3O2
CAS
873305-35-2
Smiles
C(Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccccc1)[C@@H]1CCCO1
Receptor (IC50)
Ack1: 24nM
Solubility
DMSO: 30mg/mL
Ethanol: 30mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for AIM-100, inhibitor

Home; Neuroscience; ACK

Structure of AIM-100, inhibitor

AIM-100 Inhibitor – Cat# MBS5751554

Product References and Citations for AIM-100, inhibitor

1. Mahajan K, et al. Ack1 tyrosine kinase activation correlates with pancreatic cancer progression. Am J Pathol. 2012 Apr;180 (4):1386-93.
2. Mahajan K, et al. Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer. J Biol Chem. 2012 Jun 22;287 (26):22112-22.
3. Mahajan K, et al. Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity. Prostate. 2010 Sep 1;70 (12):1274-85.

Other Notes

Small volumes of AIM-100, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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