TGN020 Inhibitor

Name: TGN020 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751563
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751563

TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1uM), the most abundant water channel in the brain. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TGN020, Inhibitor

Full Product Name

TGN020

Product Gene Name

TGN020, inhibitor

Form/Format

Powder

Purity/Purification

99.54%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

206.22

Formula

C8H6N4OS

CAS

51987-99-6

Smiles

O=C(Nc1nncs1)c1cccnc1

Receptor (IC50)

AQP4: 3.1uM

Solubility

DMSO: 8mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for TGN020, inhibitor

Home; Others

Product References and Citations for TGN020, inhibitor

1. Huber VJ, et al. Identification of aquaporin 4 inhibitors using in vitro and in silico methods. Bioorg Med Chem. 2009 Jan 1;17 (1):411-7.
2. Igarashi H, et al. Inhibition of aquaporin-4 significantly increases regional cerebral blood flow. Neuroreport. 2013 Apr 17;24 (6):324-8.

Other Notes

Small volumes of TGN020, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TGN020 purchase

MBS5751563 is an inhibitor targeting TGN020.