ABT-530 Inhibitor

Name: ABT-530 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751580
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751580

ABT-530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ABT-530, Inhibitor

Full Product Name

ABT-530

Product Gene Name

ABT-530, inhibitor

Product Synonym Names

ABT530; ABT 530; Pibrentasvir

Form/Format

Powder

Purity/Purification

99.73%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

1113.18

Formula

C57H65F5N10O8

CAS

1353900-92-1

Smiles

CO[C@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1nc2cc(F)c(cc2[nH]1)[C@H]1CC[C@@H](N1c1cc(F)c(N2CCC(CC2)c2ccc(F)cc2)c(F)c1)c1cc2[nH]c(nc2cc1F)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@@H](C)OC

Receptor (IC50)

HCV NS5A

Solubility

DMSO: 60mg/mL, need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for ABT-530, inhibitor

Home; Microbiology & virology; HCV Protease

Product References and Citations for ABT-530, inhibitor

1. Pham LV, et al. HCV Genotype 6a Escape From and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models. Gastroenterology. 2018 Jun;154 (8):2194-2208.e12.
2. Ng TI, et al. In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS5A Inhibitor Pibrentasvir. Antimicrob Agents Chemother. 2017 Apr 24;61 (5). pii: e02558-16.

Other Notes

Small volumes of ABT-530, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABT-530 purchase

MBS5751580 is an inhibitor targeting ABT-530.