• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

SR1001 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751608

MBS5751608 is an inhibitor targeting SR1001. SR 1001 is an inverse agonist for RORalpha/RORgamma (Kis: 172/111nM). More details

Please Inquire
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SR1001, Inhibitor
Full Product Name
SR1001
Product Gene Name
SR1001, inhibitor
Form/Format
Powder
Purity/Purification
99.04%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
477.4
Formula
C15H13F6N3O4S2
CAS
1335106-03-0
Smiles
CC(=O)Nc1nc(C)c(s1)S(=O)(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F
Receptor (IC50)
RORalpha: 172nM (Ki)
RORgamma: 111nM (Ki)
Solubility
DMSO: 45mg/mL
Ethanol: 45mg/mL
Water: Insoluble
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for SR1001, inhibitor

Home; Metabolism; ROR

Structure of SR1001, inhibitor

SR1001 Inhibitor – Cat# MBS5751608

Product References and Citations for SR1001, inhibitor

1. Solt LA, et al. Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand. Nature. 2011 Apr 28;472 (7344):491-4.
2. Beurel E, et al. Inflammatory T helper 17 cells promote depression-like behavior in mice. Biol Psychiatry. 2013 Apr 1;73 (7):622-30.
3. Crumbley C, et al. Regulation of expression of citrate synthase by the retinoic acid receptor-related orphan receptor alpha (RORalpha). PLoS One. 2012;7 (4):e33804.

Other Notes

Small volumes of SR1001, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000