AUT1 Inhibitor

Name: AUT1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751628
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751628

AUT1 (AUT-1) is a novel specific modulator of Kv3 channels (EC50: 4.7 and 4.9uM for Kv3.1b and Kv3.2a). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AUT1, Inhibitor

Full Product Name

AUT1

Product Gene Name

AUT1, inhibitor

Form/Format

Powder

Purity/Purification

99.43%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

341.37

Formula

C18H19N3O4

CAS

1311136-84-1

Smiles

CC[C@H]1NC(=O)N(C1=O)c1ccc(Oc2ccc(C)c(OC)c2)nc1

Receptor (IC50)

Kv3.1b: 4.7uM
Kv3.2a: 4.9uM

Solubility

DMSO: >= 250mg/mL (732.36mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for AUT1, inhibitor

Home; Membrane transporter/Ion Channel

Product References and Citations for AUT1, inhibitor

1. Rosato-Siri MD, et al. A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons. J Pharmacol Exp Ther. 2015 Sep;354 (3):251-60.
2. Brown MR, et al. Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brain stem neurons. J Neurophysiol. 2016 Jul 1;116 (1):106-21.

Other Notes

Small volumes of AUT1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AUT1 purchase

MBS5751628 is an inhibitor targeting AUT1.