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LIT-927 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751646

LIT-927 is an orally active CXCL12 neutraligand (Ki: 267nM for CXCL12 binding to CXCR4). More details

Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LIT-927, Inhibitor
Full Product Name
LIT-927
Product Gene Name
Product Synonym Names
LIT927; LIT 927
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
328.75
Formula
C17H13ClN2O3
CAS
2172879-52-4
Smiles
COc1cc(ccc1O)-c1cc(nc(=O)[nH]1)-c1ccc(Cl)cc1
Receptor (IC50)
CXCL12: 267nM (Ki)
Solubility
DMSO: 25mg/mL, 76.05mM
Water: Insoluble
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for LIT-927, inhibitor

Structure of LIT-927, inhibitor

LIT-927 Inhibitor – Cat# MBS5751646

Product References and Citations for LIT-927, inhibitor

1. Regenass P, et al. Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. J Med Chem. 2018 Sep 13;61 (17):7671-7686.

Other Notes

Small volumes of LIT-927, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LIT-927 purchase

MBS5751646 is an inhibitor targeting LIT-927.
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