pyridoxal isonicotinoyl hydrazone Inhibitor

Name: pyridoxal isonicotinoyl hydrazone Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751744
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751744

Pyridoxal isonicotinoyl hydrazine is a cell-permeable and relatively non-toxic iron (Fe3+) chelator that shows high iron chelation efficacy both in vitro and in vivo. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

pyridoxal isonicotinoyl hydrazone, Inhibitor

Full Product Name

pyridoxal isonicotinoyl hydrazone

Product Synonym Names

PIH

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

286.3

Formula

C14H14N4O3

CAS

737-86-0

Smiles

Cc1ncc(CO)c(\C=N\NC(=O)c2ccncc2)c1O

Solubility

DMSO: 28.63mg/mL, 100mM
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for pyridoxal isonicotinoyl hydrazone, inhibitor

Home; Others

Product References and Citations for pyridoxal isonicotinoyl hydrazone, inhibitor

1. Richardson DR, et al. Pyridoxal isonicotinoyl hydrazone and its analogs: potential orally effective iron-chelating agents for the treatment of iron overload disease. J Lab Clin Med. 1998 Apr;131 (4):306-15.
2. Brewer CT, et al. The Isoniazid Metabolites Hydrazine and Pyridoxal Isonicotinoyl Hydrazone Modulate Heme Biosynthesis. Toxicol Sci. 2019 Mar 1;168 (1):209-224.

Other Notes

Small volumes of pyridoxal isonicotinoyl hydrazone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5751744 is an inhibitor targeting pyridoxal isonicotinoyl hydrazone.