Rimeporide Inhibitor

Name: Rimeporide Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751748
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751748

Rimeporide (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rimeporide, Inhibitor

Full Product Name

Rimeporide

Product Synonym Names

EMD-87580

Form/Format

Powder

Purity/Purification

99.98%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

333.38

Formula

C11H15N3O5S2

CAS

187870-78-6

Smiles

Cc1cc(c(cc1C(=O)NC(N)=N)S(C)(=O)=O)S(C)(=O)=O

Receptor (IC50)

NHE-1

Solubility

DMSO: 15mg/mL, 50mM
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Rimeporide, inhibitor

Home; Membrane transporter/Ion Channel

Product References and Citations for Rimeporide, inhibitor

1. Stanbouly S, et al. Sodium hydrogen exchange 1 (NHE-1) regulates connexin 43 expression in cardiomyocytes via reverse mode sodium calcium exchange and c-Jun NH2-terminal kinase-dependent pathways. J Pharmacol Exp Ther. 2008 Oct;327 (1):105-13.
2. Cox CS Jr, et al. Improved myocardial function using a Na+/H+ exchanger inhibitor during cardioplegic arrest and cardiopulmonary bypass. Chest. 2003 Jan;123 (1):187-94.
3. F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.

Other Notes

Small volumes of Rimeporide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rimeporide purchase

MBS5751748 is an inhibitor targeting Rimeporide.