IWP-O1 Inhibitor

Name: IWP-O1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751768
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751768

IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IWP-O1, Inhibitor

Full Product Name

IWP-O1

Product Gene Name

IWP-O1, inhibitor

Form/Format

Powder

Purity/Purification

99.98%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

432.48

Formula

C26H20N6O

CAS

2074607-48-8

Smiles

O=C(Cn1nnc(c1-c1ccccc1)-c1ccncc1)Nc1ccc(cn1)-c1ccccc1

Receptor (IC50)

Porcn: 80 pM (EC50, in L-Wnt-STF cells)

Solubility

DMSO: 100mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for IWP-O1, inhibitor

Home; Stem Cells; Porcupine; IWP-O1

Product References and Citations for IWP-O1, inhibitor

1. You L, et al. Development of a triazole class of highly potent Porcn inhibitors. Bioorg Med Chem Lett. 2016 Dec 15;26 (24):5891-5895.

Other Notes

Small volumes of IWP-O1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IWP-O1 purchase

MBS5751768 is an inhibitor targeting IWP-O1.