ABX-1431 Inhibitor

Name: ABX-1431 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751776
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751776

ABX-1431 is a selective and orally available CNS-penetrant monoacylglycerol lipase (MAGL/MGLL) inhibitor (IC50: 14nM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ABX-1431, Inhibitor

Full Product Name

ABX-1431

Product Gene Name

ABX-1431, inhibitor

Form/Format

Powder

Purity/Purification

99.80%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

507.39

Formula

C20H22F9N3O2

CAS

1446817-84-0

Smiles

FC(F)(F)C(OC(=O)N1CCN(Cc2ccc(cc2N2CCCC2)C(F)(F)F)CC1)C(F)(F)F

Receptor (IC50)

hMGLL: 14nM
mMGLL: 27nM

Solubility

DMSO: 100mg/mL, 197.08mM
Water: Insoluble
Ethanol: 10mg/mL, 19.71mM
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for ABX-1431, inhibitor

Home; Metabolism; Lipase

Product References and Citations for ABX-1431, inhibitor

1. Cisar JS, et al. Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders. J Med Chem. 2018 Oct 25;61 (20):9062-9084.

Other Notes

Small volumes of ABX-1431, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABX-1431 purchase

MBS5751776 is an inhibitor targeting ABX-1431.