Y06036 Inhibitor

Name: Y06036 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751784
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751784

Y06036, a potent and selective BET inhibitor, can bind to the BRD4 (1) bromodomain (Kd: 82nM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Y06036, Inhibitor

Full Product Name

Y06036

Product Gene Name

Y06036, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

427.27

Formula

C16H15BrN2O5S

CAS

1832671-96-1

Smiles

COc1ccc(Br)cc1S(=O)(=O)Nc1cc2c(C)noc2cc1OC

Receptor (IC50)

BRD4 (1): 82nM (Kd, cell free)

Solubility

DMSO: 100mg/mL, 234mM
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Y06036, inhibitor

Home; Chromatin/Epigenetic; Epigenetic Reader Domain

Product References and Citations for Y06036, inhibitor

1. Zhang M, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC). J Med Chem. 2018 Apr 12;61 (7):3037-3058.

Other Notes

Small volumes of Y06036, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Y06036 purchase

MBS5751784 is an inhibitor targeting Y06036.