Loreclezole Inhibitor

Name: Loreclezole Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751791
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751791

Loreclezole is a selective GABAA receptor modulator and acts as a positive allosteric modulator of beta2 or beta3-subunit-containing receptors. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Loreclezole, Inhibitor

Full Product Name

Loreclezole

Form/Format

Powder

Purity/Purification

99.94%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

274.53

Formula

C10H6Cl3N3

CAS

117857-45-1

Smiles

Cl\C(=C/n1cncn1)c1ccc(Cl)cc1Cl

Receptor (IC50)

GABAA

Solubility

DMSO: 90mg/mL, 327.83mM
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Loreclezole, inhibitor

Home; Membrane transporter/Ion Channel

Product References and Citations for Loreclezole, inhibitor

1. Donnelly JL, et al. Loreclezole enhances apparent desensitization of recombinant GABAA receptor currents. Neuropharmacology. 1996;35 (9-10):1233-41.
2. Wingrove PB, et al. The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit. Proc Natl Acad Sci U S A. 1994 May 10;91 (10):4569-73.

Other Notes

Small volumes of Loreclezole, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Loreclezole purchase

MBS5751791 is an inhibitor targeting Loreclezole.