D3-betaArr Inhibitor

Name: D3-betaArr Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751796
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751796

D3-betaArr is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of beta-Arr 1 (EC50: 11.6uM) by direct TSHR activation. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

D3-betaArr, Inhibitor

Full Product Name

D3-betaArr

Product Gene Name

D3-betaArr, inhibitor

Product Synonym Names

NCGC00379308

Form/Format

Powder

Purity/Purification

99.43%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

333.43

Formula

C20H23N5

CAS

662164-09-2

Smiles

CC(Nc1nc(nc2ccccc12)N1CCNCC1)c1ccccc1

Receptor (IC50)

thyrotropin receptor (TSHR)

Solubility

DMSO: 100mg/mL (299.91mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for D3-betaArr, inhibitor

Home; Others

Product References and Citations for D3-betaArr, inhibitor

1. Neumann S, et al. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro. J Pharmacol Exp Ther. 2018 Jan;364 (1):38-45.

Other Notes

Small volumes of D3-betaArr, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for D3-betaArr purchase

MBS5751796 is an inhibitor targeting D3-betaArr.