Volinanserin Inhibitor

Name: Volinanserin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751801
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751801

Volinanserin (MDL 100907) is a potent and selective antagonist of the serotonin receptor 5-HT2 (Ki: 0.36nM) and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 adrenergic and sigma receptors. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Volinanserin, Inhibitor

Full Product Name

Volinanserin

Product Synonym Names

MDL100907; M 100907

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

373.46

Formula

C22H28FNO3

CAS

139290-65-6

Smiles

COc1cccc([C@H](O)C2CCN(CCc3ccc(F)cc3)CC2)c1OC

Receptor (IC50)

5-HT2 receptor: 0.36nM (Ki)

Solubility

DMSO: 100mg/mL (267.8mM)
Ethanol: 18mg/mL (48.2mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Volinanserin, inhibitor

Home; GPCR/G Protein; 5-HT Receptor

Product References and Citations for Volinanserin, inhibitor

1. Sorensen SM, et al. Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. J Pharmacol Exp Ther. 1993 Aug;266 (2):684-91.
2. Kehne JH, et al. Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile. J Pharmacol Exp Ther. 1996 May;277 (2):968-81.

Other Notes

Small volumes of Volinanserin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Volinanserin purchase

MBS5751801 is an inhibitor targeting Volinanserin.