GeA-69 Inhibitor

Name: GeA-69 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751810
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751810

GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86uM in ITC assays). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GeA-69, Inhibitor

Full Product Name

GeA-69

Product Gene Name

GeA-69, inhibitor

Form/Format

Powder

Purity/Purification

99.75%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

300.36

Formula

C20H16N2O

CAS

2143475-98-1

Smiles

CC(=O)Nc1ccccc1-c1cccc2c3ccccc3[nH]c12

Receptor (IC50)

PARP14: 0.86uM (Kd, in ITC assays)

Solubility

DMSO: 120mg/mL (399.53mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for GeA-69, inhibitor

Home; Chromatin/Epigenetic; PARP

Product References and Citations for GeA-69, inhibitor

1. Schuller M, et al. Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14. ACS Chem Biol. 2017 Nov 17;12 (11):2866-2874.

Other Notes

Small volumes of GeA-69, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GeA-69 purchase

MBS5751810 is an inhibitor targeting GeA-69.