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Allosteric WNK Kinase Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751857

WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1 (IC50 : 4nM) More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Allosteric WNK Kinase, Inhibitor
Full Product Name
Allosteric WNK Kinase Inhibitor
Product Synonym Names
WNK-IN-11
Form/Format
Powder
Purity/Purification
100.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
462.39
Formula
C21H21Cl2N5OS
CAS
2123489-30-3
Smiles
CNc1nc(cs1)-c1cc(C(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)c(Cl)cn1
Receptor (IC50)
WNK1: 4nM
Solubility
DMSO: 150mg/mL (324.39mM)
Water: Insoluble
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Allosteric WNK Kinase, inhibitor

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Structure of Allosteric WNK Kinase, inhibitor

Allosteric WNK Kinase Inhibitor – Cat# MBS5751857

Product References and Citations for Allosteric WNK Kinase, inhibitor

1. Yamada K, et al. Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. J Med Chem. 2017 Aug 24;60 (16):7099-7107.

Other Notes

Small volumes of Allosteric WNK Kinase, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Allosteric WNK Kinase purchase

MBS5751857 is an inhibitor targeting Allosteric WNK Kinase. Also known as Allosteric WNK Kinase Inhibitor.
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