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YF-2 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751866

YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75uM, 29.04uM and 49.31uM, respectively More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
YF-2, Inhibitor
Full Product Name
YF-2
Product Gene Name
Product Synonym Names
YF 2
Form/Format
Powder
Purity/Purification
99.19%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
430.85
Formula
C20H22ClF3N2O3
CAS
1311423-89-8
Smiles
CCOc1cccc(OCCN(C)C)c1C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
Receptor (IC50)
CBP: 2.75uM
PCAF: 29.04uM
GCN5: 29.04uM
Solubility
DMSO: 125mg/mL (290.12mM)
Water: Insoluble
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for YF-2, inhibitor

Structure of YF-2, inhibitor

YF-2 Inhibitor – Cat# MBS5751866

Product References and Citations for YF-2, inhibitor

1. FENG, Yen, et al. HISTONE ACETYLTRANSFERASE ACTIVATORS AND USES THEREOF. WO 2011072243A1.

Other Notes

Small volumes of YF-2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YF-2 purchase

MBS5751866 is an inhibitor targeting YF-2.
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