SRI31215 Inhibitor – SRI 31215

Name: SRI31215 Inhibitor; SRI 31215; MyBioSource
Brand: MyBioSource
SKU: MBS5751876
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751876

SRI 31215, a small molecule that acts as a triplex inhibitor of matriptase, hepsin and HGFA and mimics the activity of HAI-1/2, endogenous inhibitors of HGF activation with IC50s of 0.69uM, 0.65uM, 0.3uM, More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SRI 31215 (SRI31215), Inhibitor

Full Product Name

SRI 31215

Product Gene Name

SRI31215, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

533.6

Formula

C27H34F3N5O3

CAS

1832686-44-8

Smiles

OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N

Receptor (IC50)

matriptase: 0.69uM
hepsin: 0.65uM
HGFA: 0.3uM

Solubility

DMSO: Soluble
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for SRI31215, inhibitor

Home; Others

Product References and Citations for SRI31215, inhibitor

1. Owusu BY, et al. Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling. Oncotarget. 2016 May 17;7 (20):29492-506.

Other Notes

Small volumes of SRI31215, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SRI31215 purchase

MBS5751876 is an inhibitor targeting SRI31215. Also known as SRI 31215.