BI-4464 Inhibitor

Name: BI-4464 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751878
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751878

BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17nM. A PTK2 ligand for PROTAC More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BI-4464, Inhibitor

Full Product Name

BI-4464

Product Gene Name

BI-4464, inhibitor

Form/Format

Powder

Purity/Purification

97.43%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

555.56

Formula

C28H28F3N5O4

CAS

1227948-02-8

Smiles

COc1cc(ccc1Nc1ncc(c(Oc2cccc3CCC(=O)c23)n1)C(F)(F)F)C(=O)NC1CCN(C)CC1

Receptor (IC50)

PTK2/FAK: 17nM

Solubility

DMSO: 16.67mg/mL (30.01mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for BI-4464, inhibitor

Home; Angiogenesis; FAK

Product References and Citations for BI-4464, inhibitor

1. Popow J, et al. Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions. J Med Chem. 2019 Mar 14;62 (5):2508-2520.

Other Notes

Small volumes of BI-4464, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BI-4464 purchase

MBS5751878 is an inhibitor targeting BI-4464.