TG4-155 Inhibitor

Name: TG4-155 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751880
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751880

TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4nM) that is over 1000-fold less effective at EP4 (KB = 11.4uM) and a panel of other receptors and channels More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TG4-155, Inhibitor

Full Product Name

TG4-155

Product Gene Name

TG4-155, inhibitor

Form/Format

Powder

Purity/Purification

99.14%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

394.47

Formula

C23H26N2O4

CAS

1164462-05-8

Smiles

COc1cc(\C=C\C(=O)NCCn2c(C)cc3ccccc23)cc(OC)c1OC

Receptor (IC50)

EP2: 9.9nM (Ki)

Solubility

DMSO: 125mg/mL (316.89mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for TG4-155, inhibitor

Home; GPCR/G Protein; Prostaglandin Receptor

Product References and Citations for TG4-155, inhibitor

1. Jiang J, Ganesh T, Du Y, et al. Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2[J]. Proceedings of the National Academy of Sciences, 2012, 109 (8):3149-3154.
2. Jiang J, Dingledine R. Role of Prostaglandin Receptor EP2 in the Regulations of Cancer Cell Proliferation, Invasion, and Inflammation[J]. Journal of Pharmacology and Experimental Therapeutics, 2012, 344 (2):360-367.

Other Notes

Small volumes of TG4-155, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TG4-155 purchase

MBS5751880 is an inhibitor targeting TG4-155.