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DMX-5084 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751881

DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3nM.DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DMX-5084, Inhibitor
Full Product Name
DMX-5084
Product Gene Name
Form/Format
Powder
Purity/Purification
99.63%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
361.4
Formula
C21H19N3O3
CAS
2306178-56-1
Smiles
COCCOc1ccc(cc1)-c1cn(-c2ccccc2)c2nc[nH]c(=O)c12
Receptor (IC50)
MAP4K4: 3nM
Solubility
DMSO: 125mg/mL (345.89mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for DMX-5084, inhibitor

Structure of DMX-5084, inhibitor

DMX-5084 Inhibitor – Cat# MBS5751881

Product References and Citations for DMX-5084, inhibitor

1. Fiedler LR, et al. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo. Cell Stem Cell. 2019 Mar 1. pii: S1934-5909 (19)30013-X.

Other Notes

Small volumes of DMX-5084, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DMX-5084 purchase

MBS5751881 is an inhibitor targeting DMX-5084.
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