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GSK3179106 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751887

MBS5751887 is an inhibitor targeting GSK3179106. GSK3179106 is RET kinase inhibitor with an IC50 of 0.4nM More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GSK3179106, Inhibitor
Full Product Name
GSK3179106
Product Gene Name
GSK3179106, inhibitor
Form/Format
Powder
Purity/Purification
99.80%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
467.41
Formula
C22H21F4N3O4
CAS
1627856-64-7
Smiles
CCOc1cc(=O)[nH]cc1-c1ccc(CC(=O)Nc2cc(on2)C(C)(C)C(F)(F)F)c(F)c1
Receptor (IC50)
RET: 0.4nM
Solubility
DMSO: 100mg/mL (213.94mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for GSK3179106, inhibitor

Home; Apoptosis; c-RET

Structure of GSK3179106, inhibitor

GSK3179106 Inhibitor – Cat# MBS5751887

Product References and Citations for GSK3179106, inhibitor

1. Russell JP, et al. Exploring the Potential of RET Kinase Inhibition for Irritable Bowel Syndrome: A Preclinical Investigation in Rodent Models of Colonic Hypersensitivity. J Pharmacol Exp Ther. 2019 Feb;368 (2):299-307.

Other Notes

Small volumes of GSK3179106, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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