JAK3-IN-6 Inhibitor

Name: JAK3-IN-6 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751888
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751888

JAK3-IN-6 is irreversible Janus Associated Kinase 3 (JAK3) inhibitor, with an IC50 of 0.15nM More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

JAK3-IN-6, Inhibitor

Full Product Name

JAK3-IN-6

Product Gene Name

JAK3-IN-6, inhibitor

Form/Format

Powder

Purity/Purification

97.34%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

350.37

Formula

C19H18N4O3

CAS

1443235-95-7

Smiles

CCOC(=O)c1c[nH]c2ncnc(-c3cccc(NC(=O)C(C)=C)c3)c12

Receptor (IC50)

JAK3: 0.15nM

Solubility

DMSO: 60mg/mL (171.25mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for JAK3-IN-6, inhibitor

Home; Angiogenesis

Product References and Citations for JAK3-IN-6, inhibitor

1. Elwood F, et al. Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor. J Pharmacol Exp Ther. 2017 May;361 (2):229-244.
2. ARYL SULFONOHYDRAZIDES. WO2017027400A1.

Other Notes

Small volumes of JAK3-IN-6, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for JAK3-IN-6 purchase

MBS5751888 is an inhibitor targeting JAK3-IN-6.