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YKL-06-061 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751946

YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56nM/1.77nM/20.5nM for SIK1/2/3, respectively. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
YKL-06-061, Inhibitor
Full Product Name
YKL-06-061
Product Gene Name
Form/Format
Powder
Purity/Purification
99.52%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
527.66
Formula
C30H37N7O2
CAS
2172617-15-9
Smiles
COc1cc(ccc1Nc1ncc2CN(C(=O)N(C3CCC3)c2n1)c1c(C)cccc1C)N1CCN(C)CC1
Receptor (IC50)
SIK1: 6.56nM
SIK2: 1.77nM
SIK3: 20.5nM
Solubility
DMSO: 50mg/mL (94.76mM)
Water: Insoluble
(<1mg/ml refers to the product slightly soluble or insoluble)

Product References and Citations for YKL-06-061, inhibitor

1. Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19 (11):2177-2184.

Other Notes

Small volumes of YKL-06-061, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for YKL-06-061 purchase

MBS5751946 is an inhibitor targeting YKL-06-061.
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