SIS17 Inhibitor

Name: SIS17 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751988
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751988

SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83uM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SIS17, Inhibitor

Full Product Name

SIS17

Product Gene Name

SIS17, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

366.6

Formula

C21H38N2OS

CAS

2374313-54-7

Smiles

CCCCCCCCCCCCCCCCNNC(=O)c1cccs1

Receptor (IC50)

HDAC11

Solubility

DMSO: 125mg/mL (340.97mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for SIS17, inhibitor

Home; Chromatin/Epigenetic; HDAC

Product References and Citations for SIS17, inhibitor

1. Son S I, Cao J, Zhu C L, et al. Activity-Guided Design of HDAC11-Specific Inhibitors[J]. ACS Chemical Biology, 2019, 14 (7):1393-1397.

Other Notes

Small volumes of SIS17, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SIS17 purchase

MBS5751988 is an inhibitor targeting SIS17.