H3B-5942 Inhibitor

Name: H3B-5942 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751990
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751990

H3B-5942 belongs to a class of ERalpha antagonists referred to as selective estrogen receptor covalent antagonists (SERCA). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

H3B-5942, Inhibitor

Full Product Name

H3B-5942

Product Gene Name

H3B-5942, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

494.63

Formula

C31H34N4O2

CAS

2052128-15-9

Smiles

CC\C(=C(\c1ccc(OCCNC\C=C\C(=O)N(C)C)cc1)c1ccc2[nH]ncc2c1)c1ccccc1

Receptor (IC50)

Eralpha (Y537S): 0.41nM (Ki)
Eralpha (WT): 1nM (Ki)

Solubility

(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for H3B-5942, inhibitor

Home; Endocrinology/Hormones; Estrogen/progestogen Receptor

Product References and Citations for H3B-5942, inhibitor

1. Discovery of Selective Estrogen Receptor Covalent Antagonists (SERCAs) for the treatment of ERa (WT) and ERa (MUT) breast cancer.[J]. Cancer Discovery, 2018:CD-17-1229-.

Other Notes

Small volumes of H3B-5942, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for H3B-5942 purchase

MBS5751990 is an inhibitor targeting H3B-5942.