Belvarafenib Inhibitor

Name: Belvarafenib Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751991
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751991

Belvarafenib is a potent and pan RAF inhibitor with antineoplastic activity. The IC50 values of Belvarafenib are 56nM, 7nM and 5nM for B-RAF, B-RAFv600E and C-RAF respectively. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Belvarafenib, Inhibitor

Full Product Name

Belvarafenib

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

478.9

Formula

C23H16ClFN6OS

CAS

1446113-23-0

Smiles

Cc1ccc2c(Nc3cccc(Cl)c3F)nccc2c1NC(=O)c1csc2c(N)ncnc12

Receptor (IC50)

B-RAF: 56nM
B-RAFv600E: 7nM
C-RAF: 5nM

Solubility

(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Belvarafenib, inhibitor

Home; MAPK; Raf; Belvarafenib

Product References and Citations for Belvarafenib, inhibitor

1. Son J B, Jung S H, Choi Ii W, et al. Thieno[3,2-d]pyrimidine derivatives having inhibitory activity on protein kinases[J]. 2015.

Other Notes

Small volumes of Belvarafenib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Belvarafenib purchase

MBS5751991 is an inhibitor targeting Belvarafenib.