CH7057288 Inhibitor

Name: CH7057288 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751992
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751992

CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1nM, 7.8nM and 5.1nM for TRKA, TRKB and TRKC, respectively. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CH7057288, Inhibitor

Full Product Name

CH7057288

Product Gene Name

CH7057288, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

569.67

Formula

C32H31N3O5S

CAS

2095616-82-1

Smiles

Cc1cc(cc(n1)C#Cc1ccc2c3c(oc2c1)C(C)(C)c1cc(NS(C)(=O)=O)ccc1C3=O)C(=O)NC(C)(C)C

Receptor (IC50)

TRKA: 1.1nM
TRKB: 7.8nM
TRKC: 5.1nM

Solubility

DMSO: 34mg/mL (59.68mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for CH7057288, inhibitor

Home; Tyrosine Kinase/Adaptors; Trk Receptor

Product References and Citations for CH7057288, inhibitor

1. Hiroshi Tanaka, Hitoshi Sase, Toshiyuki Tsukaguchi,et al. Abstract 4179: Potent and selective TRK inhibitor CH7057288[J].10.1158/1538-7445.AM2017-4179 Published July 2017
2. Hiroshi Tanaka, et al. Abstract 4179: Potent and selective TRK inhibitor CH7057288. AACR Annual Meeting 2017; April 1-5, 2017.

Other Notes

Small volumes of CH7057288, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CH7057288 purchase

MBS5751992 is an inhibitor targeting CH7057288.