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Adavivint Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751993

MBS5751993 is an inhibitor targeting Adavivint. Also known as Adavivint (SM04690). Adavivint (SM04690) is a Wnt pathway inhibitor. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Adavivint, Inhibitor
Full Product Name
Adavivint (SM04690)
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
505.55
Formula
C29H24FN7O
CAS
1467093-03-3
Smiles
CC(C)CC(=O)Nc1cncc(c1)-c1ccc2[nH]nc(-c3nc4cncc(-c5cccc(F)c5)c4[nH]3)c2c1
Receptor (IC50)
Wnt
Solubility
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Adavivint, inhibitor

Home; Cytoskeletal Signaling; Wnt/beta-catenin

Structure of Adavivint, inhibitor

Adavivint Inhibitor – Cat# MBS5751993

Product References and Citations for Adavivint, inhibitor

1. Yazici Y, Mcalindon T E, Fleischmann R, et al. A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study[J]. Osteoarthritis & Cartilage, 2017, 25 (10):1598.

Other Notes

Small volumes of Adavivint, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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