BC2059 Inhibitor – Small Molecule Inhibitor

Name: BC2059 Inhibitor; Small Molecule Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5751999
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5751999

BC2059 is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BC2059, Inhibitor

Full Product Name

BC2059

Product Gene Name

BC2059, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

588.7

Formula

C28H36N4O6S2

CAS

1227637-23-1

Smiles

C[C@H]1C[C@@H](C)CN(C1)S(=O)(=O)c1ccc2\C(=N/O)c3ccc(cc3\C(=N/O)c2c1)S(=O)(=O)N1C[C@@H](C)C[C@@H](C)C1

Receptor (IC50)

Wnt/beta-catenin

Solubility

(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for BC2059, inhibitor

Home; Cytoskeletal Signaling; Wnt/beta-catenin

Product References and Citations for BC2059, inhibitor

1. Savvidou I, Khong T, Cuddihy A, et al. Beta-catenin inhibitor BC2059 is efficacious as monotherapy or in combination with proteasome inhibitor bortezomib in multiple myeloma[J]. Molecular Cancer Therapeutics, 2017, 16 (9):molcanther.0624.2016.
2. Fiskus W, Sharma S, Saha S, et al. Pre-clinical efficacy of combined therapy with novel beta-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells[J].Leukemia. 2015 Jun;29 (6):1267-78

Other Notes

Small volumes of BC2059, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BC2059 purchase

MBS5751999 is an inhibitor targeting BC2059.