Norcantharidin Inhibitor

Name: Norcantharidin Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752012
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752012

Norcantharidin is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Norcantharidin, Inhibitor

Full Product Name

Norcantharidin

Product Synonym Names

Endothall anhydride

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

168.15

Formula

C8H8O4

CAS

29745-04-8

Smiles

[H][C@@]12[C@H]3CC[C@H](O3)[C@]1([H])C(=O)OC2=O

Receptor (IC50)

EGFR, c-Met

Solubility

DMSO: 33mg/mL (196.25mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Norcantharidin, inhibitor

Home; Tyrosine Kinase/Adaptors; c-Met/HGFR; Norcantharidin

Product References and Citations for Norcantharidin, inhibitor

1. Qiu P, Wang S, Liu M, et al. Norcantharidin Inhibits cell growth by suppressing the expression and phosphorylation of both EGFR and c-Met in human colon cancer cells[J]. BMC Cancer, 2017, 17 (1):55.
2. Fan Y Z, Zhao Z M, Fu J Y, et al. Norcantharidin Inhibits Growth of Human Gallbladder Carcinoma Xenografted Tumors in Nude Mice by Inducing Apoptosis and Blocking the Cell Cycle in vivo[J]. Hepatobiliary & Pancreatic Diseases International, 2010, 9 (4):414-422.
3. Ye K, et al. Effect of norcantharidin on the proliferation, apoptosis, and cell cycle of human mesangialcells. Ren Fail. 2017 Nov;39 (1):458-464.

Other Notes

Small volumes of Norcantharidin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Norcantharidin purchase

MBS5752012 is an inhibitor targeting Norcantharidin.