GSK3326595 Inhibitor

Name: GSK3326595 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752096
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752096

GSK3326595 is an inhibitor of protein arginine methyltransferase 5 (PRMT5) (IC50:6.2nM.). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GSK3326595, Inhibitor

Full Product Name

GSK3326595

Product Gene Name

GSK3326595, inhibitor

Product Synonym Names

EPZ015938

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

452.55

Formula

C24H32N6O3

CAS

1616392-22-3

Smiles

CC(=O)N1CCC(CC1)Nc1cc(ncn1)C(=O)NC[C@H](O)CN1CCc2ccccc2C1

Receptor (IC50)

PRMT5: 6.2nM

Solubility

DMSO: 30mg/mL (66.29mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for GSK3326595, inhibitor

Home; Chromatin/Epigenetic; Histone Methyltransferase

Product References and Citations for GSK3326595, inhibitor

1. Gerhart S V, Kellner W A, Christine T, et al. Activation of the p53-MDM4 regulatory axis defines the anti-tumour response to PRMT5 inhibition through its role in regulating cellular splicing[J]. Scientific Reports, 2018, 8 (1):9711-.
2. WO 2016022605 A1

Other Notes

Small volumes of GSK3326595, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GSK3326595 purchase

MBS5752096 is an inhibitor targeting GSK3326595.