AlisolB Inhibitor – Alisol B

Name: AlisolB Inhibitor; Alisol B; MyBioSource
Brand: MyBioSource
SKU: MBS5752120
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752120

Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited RANKL-induced expression of NFATc1 and c-Fos, which are key transcription… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Alisol B (AlisolB), Inhibitor

Full Product Name

Alisol B

Product Gene Name

AlisolB, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

472.7

Formula

C30H48O4

CAS

18649-93-9

Smiles

[H][C@@]1(OC1(C)C)[C@@H](O)C[C@@H](C)C1=C2C[C@H](O)[C@@]3([H])[C@@]4(C)CCC(=O)C(C)(C)[C@]4([H])CC[C@]3(C)[C@@]2(C)CC1

Receptor (IC50)

RANKL

Solubility

DMSO: 95mg/mL (200.97mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for AlisolB, inhibitor

Home; Others

Product References and Citations for AlisolB, inhibitor

1. Lee J W, Kobayashi Y, Nakamichi Y, et al. Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in mice[J]. Biochemical Pharmacology, 2010, 80 (3):352-361.
2. [Alisol B inhibited complement 3a-induced human renal tubular epithelial to mesenchymal transition].

Other Notes

Small volumes of AlisolB, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AlisolB purchase

MBS5752120 is an inhibitor targeting AlisolB. Also known as Alisol B.