Cravatt Reagent Inhibitor

Name: Cravatt Reagent Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752162
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752162

Cravatt Reagent is a potent and selective MAGL inhibitor. Cravatt Reagent inhibits MAGL (IC50 = 9.1nM). MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Cravatt Reagent, Inhibitor

Full Product Name

Cravatt Reagent

Product Synonym Names

MJN110

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

462.3

Formula

C22H21Cl2N3O4

CAS

1438416-21-7

Smiles

Clc1ccc(cc1)C(N1CCN(CC1)C(=O)ON1C(=O)CCC1=O)c1ccc(Cl)cc1

Receptor (IC50)

MAGL: 9.1nM

Solubility

(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Cravatt Reagent, inhibitor

Home; Metabolism; Lipase

Product References and Citations for Cravatt Reagent, inhibitor

1. Wilkerson J L, Niphakis M J, Grim T W, et al. The selective monoacylglycerol lipase inhibitor MJN110 produces opioid sparing effects in a mouse neuropathic pain model[J]. Journal of Pharmacology and Experimental Therapeutics, 2016:jpet.115.229971.

Other Notes

Small volumes of Cravatt Reagent, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cravatt Reagent purchase

MBS5752162 is an inhibitor targeting Cravatt Reagent.