AM580 Inhibitor

Name: AM580 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752196
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752196

AM580 is a retinoic acid receptor agonist that is selective for RARalpha (IC50 : 8nM) More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AM580, Inhibitor

Full Product Name

AM580

Product Gene Name

AM580, inhibitor

Product Synonym Names

CD336; NSC608001; Ro 40-6055

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

351.44

Formula

C22H25NO3

CAS

102121-60-8

Smiles

CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O

Receptor (IC50)

RARalpha

Solubility

DMSO: 45mg/mL (128.04mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for AM580, inhibitor

Home; Metabolism; Retinoid Receptor

Product References and Citations for AM580, inhibitor

1. Cheng Y H, Utsunomiya H, Pavone M E, et al. Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms[J]. Journal of Molecular Endocrinology, 2011, 46 (2):139-153.
2. Bosch A, Bertran S P, Lu Y, et al. Reversal by RARalpha agonist Am580 of c-Myc-induced imbalance in RARalpha/RARgamma expression duringmMTV-Myc tumorigenesis[J]. Breast Cancer Research,14,4 (2012-08-24), 2012, 14 (4).

Other Notes

Small volumes of AM580, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AM580 purchase

MBS5752196 is an inhibitor targeting AM580.