D-ERYTHRO-SPHINGOSINE Inhibitor

Name: D-ERYTHRO-SPHINGOSINE Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752221
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752221

D-erythro-Sphingosine is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

D-ERYTHRO-SPHINGOSINE, Inhibitor

Full Product Name

D-ERYTHRO-SPHINGOSINE

Product Synonym Names

Erythrosphingosine; erythro-C18-Sphingosine; trans-4-Sphingenine

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

299.49

Formula

C18H37NO2

CAS

123-78-4

Smiles

CCCCCCCCCCCCC\C=C\C(O)C(N)CO

Receptor (IC50)

PKC, PP2A, Human Endogenous Metabolite

Solubility

DMSO: 250mg/mL (834.75mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for D-ERYTHRO-SPHINGOSINE, inhibitor

Home; Metabolism; PPAR

Product References and Citations for D-ERYTHRO-SPHINGOSINE, inhibitor

1. Khan W A, Dobrowsky R, El T S, et al. Protein kinase C and platelet inhibition by D-erythro-sphingosine: comparison with N,N-dimethylsphingosine and commercial preparation.[J]. Biochemical & Biophysical Research Communications, 1990, 172 (2):683-691.
2. Pham V T, Joo J E, Tian Y S, et al. A concise synthesis of a promising protein kinase C inhibitor: D-erythro-sphingosine[J]. Archives of Pharmacal Research (Seoul), 2007, 30 (1):22-27.
3. Cheng P, et al. Protein phosphatase 2A (PP2A) activation promotes axonal growth and recovery in the CNS. J Neurol Sci. 2015 Dec 15;359 (1-2):48-56.

Other Notes

Small volumes of D-ERYTHRO-SPHINGOSINE, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for D-ERYTHRO-SPHINGOSINE purchase

MBS5752221 is an inhibitor targeting D-ERYTHRO-SPHINGOSINE.