Proxyphylline Inhibitor

Proxyphylline is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor. Proxyphylline acts as a cardiac stimulant, vasodilator and bronchodilator.

1. Kukovetz W R, G P ch, Holzmann S. Overadditive synergism between theophylline, diprophylline and proxyphylline in tracheal smooth muscle relaxation[J]. Arzneimittel-Forschung, 1983, 33 (10):1450-1454.
2. Takeda K, Katano Y, Nakagawa Y, et al. EFFECTS OF AMINOPHYLLINE, PROXYPHYLLINE AND A PROXYPHYLLINE-MELILOTUS EXTRACT-RUTIN MIXTURE (THEOESBERIVEN) ON THE HEART AND THE CORONARY CIRCULATION[J]. The Japanese Journal of Pharmacology, 1977, 27 (5):709-720.
3. Rasmussen F V, Waldorff S, Madsen L. Pharmacokinetics and bronchodilatory effect of proxyphylline and theophylline.[J]. Eur J Respir Dis, 1984, 65 (1):20-27.

Small volumes of Proxyphylline, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5752230 is an inhibitor targeting Proxyphylline.