HS1371 Inhibitor

Name: HS1371 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752287
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752287

HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8nM. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HS1371, Inhibitor

Full Product Name

HS1371

Product Gene Name

HS1371, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

384.47

Formula

C24H24N4O

CAS

2158197-70-5

Smiles

Cc1ccc(Oc2ccnc3cc(ccc23)-c2cnn(c2)C2CCNCC2)cc1

Receptor (IC50)

RIP3: 20.8nM

Solubility

DMSO: 16.67mg/mL (43.36mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for HS1371, inhibitor

Home; Apoptosis; TNF

Product References and Citations for HS1371, inhibitor

1. Park HH, Park SY, Mah S et al.HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis[J]. Exp Mol Med. 2018 Sep 20;50 (9):125.

Other Notes

Small volumes of HS1371, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HS1371 purchase

MBS5752287 is an inhibitor targeting HS1371.