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ZL0420 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752288

ZL0420 is a potent and selective BRD4 inhibitor. ZL0420 reduces airway inflammation and inhibits the TLR3-dependent innate immune gene program. More details

Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ZL0420, Inhibitor
Full Product Name
ZL0420
Product Gene Name
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
296.32
Formula
C16H16N4O2
CAS
2229039-45-4
Smiles
Cc1cc(\N=N\c2ccc3NC(=O)CCc3c2)c(N)cc1O
Receptor (IC50)
BRD4
Solubility
DMSO: 59mg/mL (199.11mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Structure of ZL0420, inhibitor

ZL0420 Inhibitor – Cat# MBS5752288

Product References and Citations for ZL0420, inhibitor

1. Tian B, Liu Z, Litvinov J,et al.Efficacy of Novel Highly Specific Bromodomain-Containing Protein 4 Inhibitors in Innate Inflammation-Driven Airway Remodeling[J].Am J Respir Cell Mol Biol. 2019 Jan;60 (1):68-83.

Other Notes

Small volumes of ZL0420, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZL0420 purchase

MBS5752288 is an inhibitor targeting ZL0420.
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