Rafoxanide Inhibitor

Name: Rafoxanide Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752312
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752312

Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rafoxanide, Inhibitor

Full Product Name

Rafoxanide

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

626.01

Formula

C19H11Cl2I2NO3

CAS

22662-39-1

Smiles

Oc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccc(Cl)cc2)c(Cl)c1

Receptor (IC50)

CDK3/4

Solubility

DMSO: 31mg/mL (49.52mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Rafoxanide, inhibitor

Home; Cell Cycle/Checkpoint; CDK

Product References and Citations for Rafoxanide, inhibitor

1. Shi X, Li H, Shi A et al.Discovery of rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer[J].Oncol Rep. 2018 Sep;40 (3):1592-1600.
2. Xiao W, Xu Z, Chang S, et al. Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway[J]. Cancer Letters, 2019, 444:45-59.

Other Notes

Small volumes of Rafoxanide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rafoxanide purchase

MBS5752312 is an inhibitor targeting Rafoxanide.