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Necrosulfonamide Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752346

Necrosulfonamide is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Necrosulfonamide, Inhibitor
Full Product Name
Necrosulfonamide
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
461.47
Formula
C18H15N5O6S2
CAS
432531-71-0
Smiles
COc1nccnc1NS(=O)(=O)c1ccc(NC(=O)\C=C\c2ccc(s2)[N+]([O-])=O)cc1
Solubility
DMSO: 9.2mg/mL (20mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Other Notes

Small volumes of Necrosulfonamide, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Necrosulfonamide purchase

MBS5752346 is an inhibitor targeting Necrosulfonamide.
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