AZD6280 Inhibitor

Name: AZD6280 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752352
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752352

AZD6280 is a novel, subtype-selective GABAAalpha2/3 receptor positive modulators, used for treatment of generalized anxiety disorder. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AZD6280, Inhibitor

Full Product Name

AZD6280

Product Gene Name

AZD6280, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

366.41

Formula

C20H22N4O3

CAS

942436-93-3

Smiles

CCCNC(=O)c1nnc2c(cccc2c1N)-c1cc(OC)ccc1OC

Receptor (IC50)

GABAA

Solubility

DMSO: 62.5mg/mL (170.57mM), Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for AZD6280, inhibitor

Home; Membrane transporter/Ion Channel

Product References and Citations for AZD6280, inhibitor

1. Jucaite A, Cselényi, Zsolt, Lappalainen J, et al. GABAAreceptor occupancy by subtype selective GABAAalpha2,3modulators: PET studies in humans[J]. Psychopharmacology, 2017, 234 (4):707-716.
2. Te Beek E T, Chen X, Jacobs G E, et al. The effects of the nonselective benzodiazepine lorazepam and the alpha2 /alpha3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels.[J]. Clin Pharmacol Drug Dev, 2015, 4 (2):149-154.

Other Notes

Small volumes of AZD6280, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD6280 purchase

MBS5752352 is an inhibitor targeting AZD6280.