FB23-2 Inhibitor

Name: FB23-2 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752354
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752354

FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor (IC50 : 2.6uM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FB23-2, Inhibitor

Full Product Name

FB23-2

Product Gene Name

FB23-2, inhibitor

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

392.24

Formula

C18H15Cl2N3O3

CAS

2243736-45-8

Smiles

Cc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(=O)NO)c(Cl)c1

Receptor (IC50)

FTO

Solubility

DMSO: 62.5mg/mL (159.34mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for FB23-2, inhibitor

Home; Others

Product References and Citations for FB23-2, inhibitor

1. Huang Y, Su R, Sheng Y, et al. Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia[J]. Cancer Cell, 2019, 35 (4):677-691.e10.
2. Inge V D W, Jamieson C. The Yin and Yang of RNA Methylation: An Imbalance of Erasers Enhances Sensitivity to FTO Demethylase Small-Molecule Targeting in Leukemia Stem Cells[J]. Cancer Cell, 2019, 35 (4):540-541.

Other Notes

Small volumes of FB23-2, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FB23-2 purchase

MBS5752354 is an inhibitor targeting FB23-2.