Alagebrium chloride Inhibitor

Name: Alagebrium chloride Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752356
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752356

Alagebrium Chloride is an advanced glycation end product (AGE) inhibitor, and has proven effective in reducing systolic blood pressure and providing therapeutic benefit for patients with diastolic More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Alagebrium chloride, Inhibitor

Full Product Name

Alagebrium chloride

Product Synonym Names

ALT711

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

267.77

Formula

C13H14ClNOS

CAS

341028-37-3

Smiles

[Cl-].Cc1sc[n+](CC(=O)c2ccccc2)c1C

Receptor (IC50)

AGE

Solubility

DMSO: 25mg/mL (93.36mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Alagebrium chloride, inhibitor

Home; Others

Product References and Citations for Alagebrium chloride, inhibitor

1. Jin-Bae K, Byeong-Wook S, Sungha P, et al. Alagebrium Chloride, a Novel Advanced Glycation End-Product Cross Linkage Breaker, Inhibits Neointimal Proliferation in a Diabetic Rat Carotid Balloon Injury Model[J]. Korean Circulation Journal, 2010, 40 (10):520-.
2. Watson A M D, Gray S P, Jiaze L, et al. Alagebrium Reduces Glomerular Fibrogenesis and Inflammation Beyond Preventing RAGE Activation in Diabetic Apolipoprotein E Knockout Mice[J]. Diabetes, 2012, 61 (8):2105-2113.
3. Wang H, et al. Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats. Am J Physiol Heart Circ Physiol. 2015 Oct;309 (7):H1130-40.

Other Notes

Small volumes of Alagebrium chloride, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Alagebrium chloride purchase

MBS5752356 is an inhibitor targeting Alagebrium chloride.