Ombitasvir Inhibitor

Name: Ombitasvir Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752370
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752370

Ombitasvir is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A).with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Ombitasvir, Inhibitor

Full Product Name

Ombitasvir

Product Synonym Names

ABT-267

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

894.11

Formula

C50H67N7O8

CAS

1258226-87-7

Smiles

COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)Nc1ccc(cc1)[C@@H]1CC[C@H](N1c1ccc(cc1)C(C)(C)C)c1ccc(NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)OC)C(C)C)cc1

Receptor (IC50)

HCV genotypes 1 to 5: 0.82pM-19.3pM (EC50)
HCV genotype 6a: 366pM (EC50)

Solubility

DMSO: 33mg/mL (36.91mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Ombitasvir, inhibitor

Home; Microbiology & virology; HCV Protease

Product References and Citations for Ombitasvir, inhibitor

1. Krishnan P, Beyer J, Mistry N,et al.in vitro and in vivo antiviral activity and resistance profile of ombitasvir, an inhibitor of hepatitis c virus ns5a[J].Antimicrob Agents Chemother. 2015 Feb;59 (2):979-87.
2. Keating, Gillian M. Ombitasvir/Paritaprevir/Ritonavir: A Review in Chronic HCV Genotype 4 Infection[J]. Drugs, 2016, 76 (12):1203-1211.

Other Notes

Small volumes of Ombitasvir, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ombitasvir purchase

MBS5752370 is an inhibitor targeting Ombitasvir.