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Piclidenoson Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752394

Piclidenoson, a selective agonist of adenosine A3 receptor (EC50 values of 0.11uM), induces robust anti-inflammatory effect in psoriasis patients. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Piclidenoson, Inhibitor
Full Product Name
Piclidenoson
Product Synonym Names
IB-MECA; CF-101
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
510.29
Formula
C18H19IN6O4
CAS
152918-18-8
Smiles
CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12
Receptor (IC50)
A3
Solubility
DMSO: 45mg/mL (88.19mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product References and Citations for Piclidenoson, inhibitor

1. Cohen S, Barer F, Itzhak I, et al. Inhibition of IL-17 and IL-23 in Human Keratinocytes by the A 3 Adenosine Receptor Agonist Piclidenoson[J]. Journal of Immunology Research, 2018, 2018 (1):1-8
.2. Abedi H, Aghaei M, Panjehpour M, et al. Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines[J]. Tumor Biology, 2014, 35 (11):11027-11039.

Other Notes

Small volumes of Piclidenoson, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Piclidenoson purchase

MBS5752394 is an inhibitor targeting Piclidenoson.
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