Diphenyleneiodonium chloride Inhibitor

Name: Diphenyleneiodonium chloride Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752396
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752396

Diphenyleneiodonium chloride (DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50nM and 0.3uM, respectively),and displays broad-spectrum bactericidal activity. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Diphenyleneiodonium chloride, Inhibitor

Full Product Name

Diphenyleneiodonium chloride

Product Synonym Names

DPI

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

314.55

Formula

C12H8ClI

CAS

4673-26-1

Smiles

[Cl-].[I+]1c2ccccc2-c2ccccc12

Receptor (IC50)

iNOS: 50nM
eNOS: 0.3uM

Solubility

DMSO: 6mg/mL (19.07mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Diphenyleneiodonium chloride, inhibitor

Home; Immunology/Inflammation; NOS

Product References and Citations for Diphenyleneiodonium chloride, inhibitor

1. Singh A K, Thakare R, Karaulia P, et al. Biological evaluation of diphenyleneiodonium chloride (DPIC) as a potential drug candidate for treatment of non-tuberculous mycobacterial infections[J]. Journal of Antimicrobial Chemotherapy, 2017.
2. Stuehr D J, Fasehun O A, Kwon N S, et al. Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs.[J]. The FASEB Journal, 1991, 5 (1):98-103.

Other Notes

Small volumes of Diphenyleneiodonium chloride, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Diphenyleneiodonium chloride purchase

MBS5752396 is an inhibitor targeting Diphenyleneiodonium chloride.