Encenicline Inhibitor

Name: Encenicline Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752398
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752398

Encenicline is a selective alpha7 nicotinic acetylcholine receptor (nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Encenicline, Inhibitor

Full Product Name

Encenicline

Product Synonym Names

EVP-6124

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

320.84

Formula

C16H17ClN2OS

CAS

550999-75-2

Smiles

Clc1cccc2cc(sc12)C(=O)N[C@H]1CN2CCC1CC2

Receptor (IC50)

nAChR

Solubility

(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Encenicline, inhibitor

Home; Neuroscience; AChR

Product References and Citations for Encenicline, inhibitor

1. Prickaerts J, van Goethem NP, Chesworth R,et al.EVP-6124, a novel and selective alpha7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of alpha7 nicotinic acetylcholine receptors[J].Neuropharmacology. 2012 Feb;62 (2):1099-110.
2. Hayward A, Adamson L, Neill J C. Partial agonism at the alpha7 nicotinic acetylcholine receptor improves attention, impulsive action and vigilance in low attentive rats[J]. European Neuropsychopharmacology, 2017, 27 (4):325-335.

Other Notes

Small volumes of Encenicline, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Encenicline purchase

MBS5752398 is an inhibitor targeting Encenicline.