EGT1442 Inhibitor

Name: EGT1442 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5752420
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752420

EGT1442 is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 5.6uM and 2nM for human SGLT1 and SGLT2, respectively More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EGT1442, Inhibitor

Full Product Name

EGT1442

Product Gene Name

EGT1442, inhibitor

Product Synonym Names

Bexagliflozin; EGT0001442; THR-1442

Form/Format

Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Molecular Weight

464.94

Formula

C24H29ClO7

CAS

1118567-05-7

Smiles

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCOC3CC3)cc2)c1

Receptor (IC50)

SGLT2

Solubility

DMSO: 100mg/mL (215.08mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for EGT1442, inhibitor

Home; GPCR/G Protein; SGLT

Product References and Citations for EGT1442, inhibitor

1. Zhang W, Welihinda A, Mechanic J, et al. EGT1442, a potent and selective SGLT2 inhibitor, attenuates blood glucose and HbA1c levels in db/db mice and prolongs the survival of stroke-prone rats[J]. Pharmacological Research, 2011, 63 (4):284-293.

Other Notes

Small volumes of EGT1442, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EGT1442 purchase

MBS5752420 is an inhibitor targeting EGT1442.