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Aramchol Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5752442

Aramchol, also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholesterol crystals in a dose-dependent manner. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Aramchol, Inhibitor
Full Product Name
Aramchol
Product Synonym Names
C20-FABAC
Form/Format
Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder; -80 degree C for 2 years in solvent
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.
Molecular Weight
702.1
Formula
C44H79NO5
CAS
246529-22-6
Smiles
[H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)C[C@]2([H])C[C@H](CC[C@]12C)NC(=O)CCCCCCCCCCCCCCCCCCC
Solubility
DMSO: 53.33mg/mL (75.96mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Product Categories/Family for Aramchol, inhibitor

Structure of Aramchol, inhibitor

Aramchol Inhibitor – Cat# MBS5752442

Product References and Citations for Aramchol, inhibitor

1. Safadi R, Konikoff F M, Mahamid M, et al. The Fatty Acid-Bile Acid Conjugate Aramchol Reduces Liver Fat Content in Patients With Nonalcoholic Fatty Liver Disease[J]. Clinical Gastroenterology and Hepatology, 2014, 12 (12):2085-2091.e1.
2. Eshraghian A. Current and emerging pharmacological therapy for non-alcoholic fatty liver disease[J]. World Journal of Gastroenterology, 2017, 23 (42):7495-7504.
3. Iruarrizaga-Lejarreta M, et al. Role of Aramchol in steatohepatitis and fibrosis in mice. Hepatol Commun. 2017 Nov;1 (9):911-927.

Other Notes

Small volumes of Aramchol, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Aramchol purchase

MBS5752442 is an inhibitor targeting Aramchol.
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